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In Drug search, users can search candidate drugs/compounds that associate with Shelterin.
Result
This table shows chemicals/drugs, their mechanism of action(MOA) and association with shelterin.
Chemical | Cancer | MOA | Association | ||
---|---|---|---|---|---|
MS-275 | ESCA | HDAC inhibitor | positively | ||
MS-275 | LGG | HDAC inhibitor | positively | ||
MS-275 | KICH | HDAC inhibitor | positively | ||
Nilotinib | KIRP | Abl kinase inhibitor|Bcr-Abl kinase inhibitor | positively | ||
Nilotinib | PCPG | Abl kinase inhibitor|Bcr-Abl kinase inhibitor | positively | ||
Nilotinib | UCS | Abl kinase inhibitor|Bcr-Abl kinase inhibitor | positively | ||
Nilotinib | GBM | Abl kinase inhibitor|Bcr-Abl kinase inhibitor | positively | ||
Nilotinib | LGG | Abl kinase inhibitor|Bcr-Abl kinase inhibitor | positively | ||
NSC-87877 | LGG | SHP1/2 PTPase inhibitor | positively | ||
NSC-87877 | PAAD | SHP1/2 PTPase inhibitor | positively | ||
NSC-87877 | CHOL | SHP1/2 PTPase inhibitor | positively | ||
NSC-87877 | PCPG | SHP1/2 PTPase inhibitor | positively | ||
NSC-87877 | THYM | SHP1/2 PTPase inhibitor | positively | ||
NSC-87877 | GBM | SHP1/2 PTPase inhibitor | positively | ||
NSC-87877 | UVM | SHP1/2 PTPase inhibitor | positively | ||
NU-7441 | UCEC | DNA dependent protein kinase inhibitor | positively | ||
NU-7441 | SARC | DNA dependent protein kinase inhibitor | positively | ||
NU-7441 | KICH | DNA dependent protein kinase inhibitor | positively | ||
NU-7441 | PCPG | DNA dependent protein kinase inhibitor | positively | ||
NU-7441 | UVM | DNA dependent protein kinase inhibitor | positively | ||