Quick search
In Drug search, users can search candidate drugs/compounds that associate with Shelterin.
Result
This table shows chemicals/drugs, their mechanism of action(MOA) and association with shelterin.
| Chemical | Cancer | MOA | Association | ||
|---|---|---|---|---|---|
| Midostaurin | UVM | FLT3 inhibitor|KIT inhibitor|PKC inhibitor | positively | ||
| Midostaurin | LGG | FLT3 inhibitor|KIT inhibitor|PKC inhibitor | positively | ||
| Midostaurin | GBM | FLT3 inhibitor|KIT inhibitor|PKC inhibitor | positively | ||
| Mitomycin-C | LGG | DNA alkylating agent|DNA synthesis inhibitor | positively | ||
| Mitomycin-C | ACC | DNA alkylating agent|DNA synthesis inhibitor | positively | ||
| Mitomycin-C | PCPG | DNA alkylating agent|DNA synthesis inhibitor | positively | ||
| Mitomycin-C | GBM | DNA alkylating agent|DNA synthesis inhibitor | positively | ||
| MK-2206 | KICH | AKT inhibitor | positively | ||
| MK-2206 | PCPG | AKT inhibitor | positively | ||
| MK-2206 | TGCT | AKT inhibitor | positively | ||
| MK-2206 | GBM | AKT inhibitor | positively | ||
| MS-275 | KIRP | HDAC inhibitor | positively | ||
| MS-275 | BLCA | HDAC inhibitor | positively | ||
| MS-275 | PCPG | HDAC inhibitor | positively | ||
| MS-275 | SKCM | HDAC inhibitor | positively | ||
| MS-275 | UVM | HDAC inhibitor | positively | ||
| MS-275 | TGCT | HDAC inhibitor | positively | ||
| MS-275 | PRAD | HDAC inhibitor | positively | ||
| MS-275 | GBM | HDAC inhibitor | positively | ||
| MS-275 | HNSC | HDAC inhibitor | positively | ||