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In Drug search, users can search candidate drugs/compounds that associate with Shelterin.

Result

This table shows chemicals/drugs, their mechanism of action(MOA) and association with shelterin.

Chemical Cancer MOA Association
NU-7441 TGCT DNA dependent protein kinase inhibitor positively
Nutlin-3a TGCT MDM2 antagonist positively
NVP-BEZ235 SARC mTOR inhibitor|PI3K inhibitor positively
NVP-BEZ235 UVM mTOR inhibitor|PI3K inhibitor positively
NVP-BEZ235 PCPG mTOR inhibitor|PI3K inhibitor positively
NVP-BEZ235 KICH mTOR inhibitor|PI3K inhibitor positively
NVP-TAE684 PAAD ALK tyrosine kinase receptor inhibitor positively
NVP-TAE684 UCEC ALK tyrosine kinase receptor inhibitor positively
NVP-TAE684 GBM ALK tyrosine kinase receptor inhibitor positively
NVP-TAE684 OV ALK tyrosine kinase receptor inhibitor positively
NVP-TAE684 LGG ALK tyrosine kinase receptor inhibitor positively
NVP-TAE684 UVM ALK tyrosine kinase receptor inhibitor positively
NVP-TAE684 KICH ALK tyrosine kinase receptor inhibitor positively
NVP-TAE684 THYM ALK tyrosine kinase receptor inhibitor positively
NVP-TAE684 PCPG ALK tyrosine kinase receptor inhibitor positively
Obatoclax-Mesylate PCPG BCL2 antagonist positively
Obatoclax-Mesylate ACC BCL2 antagonist positively
Obatoclax-Mesylate TGCT BCL2 antagonist positively
Obatoclax-Mesylate UVM BCL2 antagonist positively
OSI-906 UVM IGF-1R inhibitor positively
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