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In Drug search, users can search candidate drugs/compounds that associate with Shelterin.
Result
This table shows chemicals/drugs, their mechanism of action(MOA) and association with shelterin.
Chemical | Cancer | MOA | Association | ||
---|---|---|---|---|---|
NU-7441 | TGCT | DNA dependent protein kinase inhibitor | positively | ||
Nutlin-3a | TGCT | MDM2 antagonist | positively | ||
NVP-BEZ235 | SARC | mTOR inhibitor|PI3K inhibitor | positively | ||
NVP-BEZ235 | UVM | mTOR inhibitor|PI3K inhibitor | positively | ||
NVP-BEZ235 | PCPG | mTOR inhibitor|PI3K inhibitor | positively | ||
NVP-BEZ235 | KICH | mTOR inhibitor|PI3K inhibitor | positively | ||
NVP-TAE684 | PAAD | ALK tyrosine kinase receptor inhibitor | positively | ||
NVP-TAE684 | UCEC | ALK tyrosine kinase receptor inhibitor | positively | ||
NVP-TAE684 | GBM | ALK tyrosine kinase receptor inhibitor | positively | ||
NVP-TAE684 | OV | ALK tyrosine kinase receptor inhibitor | positively | ||
NVP-TAE684 | LGG | ALK tyrosine kinase receptor inhibitor | positively | ||
NVP-TAE684 | UVM | ALK tyrosine kinase receptor inhibitor | positively | ||
NVP-TAE684 | KICH | ALK tyrosine kinase receptor inhibitor | positively | ||
NVP-TAE684 | THYM | ALK tyrosine kinase receptor inhibitor | positively | ||
NVP-TAE684 | PCPG | ALK tyrosine kinase receptor inhibitor | positively | ||
Obatoclax-Mesylate | PCPG | BCL2 antagonist | positively | ||
Obatoclax-Mesylate | ACC | BCL2 antagonist | positively | ||
Obatoclax-Mesylate | TGCT | BCL2 antagonist | positively | ||
Obatoclax-Mesylate | UVM | BCL2 antagonist | positively | ||
OSI-906 | UVM | IGF-1R inhibitor | positively | ||