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In Drug search, users can search candidate drugs/compounds that associate with Shelterin.
Result
This table shows chemicals/drugs, their mechanism of action(MOA) and association with shelterin.
Chemical | Cancer | MOA | Association | ||
---|---|---|---|---|---|
Lenalidomide | LGG | anticancer agent | positively | ||
LFM-A13 | THYM | Bruton's tyrosine kinase (BTK) inhibitor | positively | ||
LFM-A13 | UVM | Bruton's tyrosine kinase (BTK) inhibitor | positively | ||
LFM-A13 | UCEC | Bruton's tyrosine kinase (BTK) inhibitor | positively | ||
Metformin | KICH | insulin sensitizer | positively | ||
Metformin | TGCT | insulin sensitizer | positively | ||
Metformin | PRAD | insulin sensitizer | positively | ||
Metformin | KIRP | insulin sensitizer | positively | ||
Metformin | LUAD | insulin sensitizer | positively | ||
Metformin | UVM | insulin sensitizer | positively | ||
Metformin | ACC | insulin sensitizer | positively | ||
Metformin | PCPG | insulin sensitizer | positively | ||
Methotrexate | TGCT | dihydrofolate reductase inhibitor | positively | ||
Methotrexate | KIRP | dihydrofolate reductase inhibitor | positively | ||
MG-132 | THYM | proteasome inhibitor | positively | ||
MG-132 | PCPG | proteasome inhibitor | positively | ||
MG-132 | SARC | proteasome inhibitor | positively | ||
MG-132 | UVM | proteasome inhibitor | positively | ||
MG-132 | UCEC | proteasome inhibitor | positively | ||
Midostaurin | PCPG | FLT3 inhibitor|KIT inhibitor|PKC inhibitor | positively | ||