Quick search
In Drug search, users can search candidate drugs/compounds that associate with Shelterin.
Result
This table shows chemicals/drugs, their mechanism of action(MOA) and association with shelterin.
| Chemical | Cancer | MOA | Association | ||
|---|---|---|---|---|---|
| Pyrimethamine | UCS | dihydrofolate reductase inhibitor | positively | ||
| Pyrimethamine | LGG | dihydrofolate reductase inhibitor | positively | ||
| Pyrimethamine | PCPG | dihydrofolate reductase inhibitor | positively | ||
| Pyrimethamine | ACC | dihydrofolate reductase inhibitor | positively | ||
| QS11 | TGCT | ADP-ribosylation factor 1 (ARFGAP1) inhibitor | positively | ||
| QS11 | BRCA | ADP-ribosylation factor 1 (ARFGAP1) inhibitor | positively | ||
| QS11 | ACC | ADP-ribosylation factor 1 (ARFGAP1) inhibitor | positively | ||
| QS11 | PCPG | ADP-ribosylation factor 1 (ARFGAP1) inhibitor | positively | ||
| Rapamycin | UVM | mTOR inhibitor | positively | ||
| Rapamycin | GBM | mTOR inhibitor | positively | ||
| Rapamycin | SARC | mTOR inhibitor | positively | ||
| Rapamycin | LGG | mTOR inhibitor | positively | ||
| Rapamycin | PCPG | mTOR inhibitor | positively | ||
| RDEA119 | GBM | MEK inhibitor | positively | ||
| RDEA119 | PAAD | MEK inhibitor | positively | ||
| RDEA119 | THYM | MEK inhibitor | positively | ||
| RDEA119 | ESCA | MEK inhibitor | positively | ||
| RO-3306 | SARC | CDK inhibitor | positively | ||
| RO-3306 | UCEC | CDK inhibitor | positively | ||
| RO-3306 | KICH | CDK inhibitor | positively | ||