Quick search
In Drug search, users can search candidate drugs/compounds that associate with Shelterin.
Result
This table shows chemicals/drugs, their mechanism of action(MOA) and association with shelterin.
| Chemical | Cancer | MOA | Association | ||
|---|---|---|---|---|---|
| CHIR-99021 | BRCA | glycogen synthase kinase inhibitor | positively | ||
| CHIR-99021 | HNSC | glycogen synthase kinase inhibitor | positively | ||
| CHIR-99021 | LUSC | glycogen synthase kinase inhibitor | positively | ||
| CHIR-99021 | GBM | glycogen synthase kinase inhibitor | positively | ||
| CI-1040 | DLBC | MEK inhibitor | positively | ||
| CI-1040 | SARC | MEK inhibitor | positively | ||
| CI-1040 | ESCA | MEK inhibitor | positively | ||
| CI-1040 | GBM | MEK inhibitor | positively | ||
| Cisplatin | TGCT | DNA alkylating agent|DNA synthesis inhibitor | positively | ||
| Cisplatin | ACC | DNA alkylating agent|DNA synthesis inhibitor | positively | ||
| Cisplatin | PCPG | DNA alkylating agent|DNA synthesis inhibitor | positively | ||
| CMK | UVM | RSK inhibitor | positively | ||
| Cyclopamine | TGCT | Hedgehog inhibitor | positively | ||
| Cyclopamine | BRCA | Hedgehog inhibitor | positively | ||
| Cyclopamine | PCPG | Hedgehog inhibitor | positively | ||
| Cytarabine | DLBC | ribonucleotide reductase inhibitor | positively | ||
| Cytarabine | KICH | ribonucleotide reductase inhibitor | positively | ||
| Cytarabine | PCPG | ribonucleotide reductase inhibitor | positively | ||
| Cytarabine | GBM | ribonucleotide reductase inhibitor | positively | ||
| Dasatinib | PCPG | Bcr-Abl kinase inhibitor|ephrin inhibitor|KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|src inhibitor|tyrosine kinase inhibitor | positively | ||